2,4,6-trihydroxyphenanthrene: a new trans-resveratrol derivative detected in red wine after UV irradiation.

By Luciana Mosca and Alberto Macone
T2,4,6-trihydroxyphenanthrene (THP) results from cyclization of the trans-to the cis-isomer of resveratrol one of the most abundant polyphenols in red grapes and red wine. It has been demonstrated that THP can induce DNA damage through a pro-oxidant mechanism. On the other hand, due to the extended delocalization and conjugation of the πelectrons over the entire molecule, THP displays a significantly increased antioxidant activity compared to RSV with potential benefits on human health. Whatever the effect of THP on human health, it becomes important to establish its actual presence not only in RSV-containing food and beverages but even in cosmetics that, by their nature, are subject to UV radiation. Find out more

How efficient is resveratrol as an antioxidant of the Mediterranean diet, towards alterations during the aging process?

By Paula Silva, Antoni Sureda, Josep A. Tur, Pierre Andreoletti, Mustapha Cherkaoui-Malki and Norbert Latruffe
This post is related with a paper written by me and my colleagues and deals to how efficient is resveratrol towards alterations during the aging process; obtained from recent data of clinical trials, preclinical studies, and cell culture approach; especially resveratrol protecting effect on brain aging of elderly; its role on the microglial cells playing a central role in the neuro-inflammation; and in its anti-inflammatory effects on ocular diseases. This is also a good topic to discuss in the next Science & Wine conference “Wine Consumption in the Mediterranean Diet: A clarification about health effects” be held in Porto at June 4 of 2020. Find out more

Interactive effects of the rootstock and the deficit irrigation technique on wine composition, nutraceutical potential, aromatic profile, and sensory attributes under semiarid and water limiting conditions

By Pascual Romero and Josefa Navarro
This post is a summary of a study carried out to analyse the effects of the rootstock, irrigation method, and their interaction on the final wine composition, volatile aromatic profile, and wine sensory attributes. According with the results authors recommend the use of low vigor rootstocks and deficit irrigation techniques with small water volumes to improve Monastrell wine quality, and as a measure to adapt vineyards to climate change under semiarid and water limiting conditions. Find out more


My name is Paula Silva and I decided to accept this challenge of being the responsible editor of this blog because I believe that science must be shared and because it is very important to update public with information’s based in scientific evidences. My purpose is to serve people who wants to know more about wine by fostering networking, education, discussion, and exchange. I hope that this blog can be a resource on current and emerging issues in wine research area. Find out more